Regiospecific preparation of 1,4,5-trisubstituted pyrazoles from 2-(1H-1,2,3-benzotriazol-1-yl)-3-(4-aryl)-2-propenals

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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(2’-n-BUTYLBENZOFURAN-3’-YL)-5-ARYL-4, 5-DIHYDRO-1H-PYRAZOLES.

           3-(2’-n-butylbenzofuran-3’-yl)-5-aryl-4, 5-dihydro-1H-pyrazoles (4a-4k) have been synthesized. The synthesized products have been assayed for their antimicrobial activity against Gram+ve,      Gram-ve bacteria and fungi. All the synthesized products were assigned with IR, 1HNMR, Mass Spectra, TLC, and elemental analysis. Some of the products showed moderate activi...

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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(2’-n-BUTYLBENZOFURAN-3’-YL)-5-ARYL-4, 5-DIHYDRO-1H-PYRAZOLES.

           3-(2’-n-butylbenzofuran-3’-yl)-5-aryl-4, 5-dihydro-1H-pyrazoles (4a-4k) have been synthesized. The synthesized products have been assayed for their antimicrobial activity against Gram+ve,      Gram-ve bacteria and fungi. All the synthesized products were assigned with IR, 1HNMR, Mass Spectra, TLC, and elemental analysis. Some of the products showed moderate activi...

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2-(1H-Benzotriazol-1-yl)-1-(furan-2-yl)ethanol

In the title compound, C(12)H(11)N(3)O(2), the benzotriazole ring system is approximately planar [maximum deviation = 0.008 (1) Å] and its mean plane is oriented at a dihedral angle of 24.05 (4)° with respect to the furan ring. In the crystal, O-H⋯N hydrogen bonds link the mol-ecules into chains along the ac diagonal. π-π stacking between the furan rings, between the triazole and benzene rings,...

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1-(1H-1,2,3-Benzotriazol-1-yl)-2-(4-meth­oxy­phen­yl)ethanone

In the title compound, C(15)H(13)N(3)O(2), the dihedral angle between the benzotriazole ring system (r.m.s. deviation = 0.0124 Å) and the benzene ring is 76.21 (3)°. The meth-oxy C atom deviates from its benzene ring plane by 0.063 (2)Å. In the crystal, inversion dimers linked by pairs of C-H⋯O hydrogen bonds generate R(2) (2)(12) loops.

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2-(1H-Benzotriazol-1-yl)-1-phenyl­ethanol

In the title compound, C(14)H(13)N(3)O, the benzotriazole ring is oriented at a dihedral angle of 13.43 (4)° with respect to the phenyl ring. In the crystal structure, inter-molecular O-H⋯N hydrogen bonds link the mol-ecules into chains along the b axis. Aromatic π-π contacts between benzene rings and between triazole and benzene rings [centroid-centroid distances = 3.8133 (8) and 3.7810 (8) Å,...

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ژورنال

عنوان ژورنال: Arkivoc

سال: 2007

ISSN: 1551-7012

DOI: 10.3998/ark.5550190.0008.102